Skin cancer is the uncontrolled growth of abnormal skin cells. It occurs when damaged skin cells do not replicate correctly during the normal course of repair.
These new irregular cells can trigger DNA mutations or genetic defects that multiply rapidly and form malignant tumours.
Skin cancers account for around 80% of all newly diagnosed cancers. Approximately, 66% of Australians will be diagnosed with skin cancer, almost three times the rate seen in the US or the UK.
Annually, over 750,000 people are treated for non-melanoma skin cancers in Australia. These non-melanoma skin cancers are twice as common in men.
Melanoma skin cancer affects over 12,000 Australians annually, it is the most common cancer among Australians between 15-44 years
There are six types of skin cancer, these are:
Actinic keratoses (AK) also called solar keratoses are scaly, crusty growths (lesions) caused by damage from the sun’s ultraviolet (UV) rays.
They typically appear on sun-exposed areas such as the face, bald scalp, lips, and the back of the hands, and are often elevated, rough in texture, and resemble warts.
Most become red, but some will be tan, pink, and/or flesh-toned. If left untreated, up to 10% of AKs develop into squamous cell carcinoma (SCC), the second most common form of skin cancer. In rare instances, AKs may also turn into basal cell carcinomas, the most common form of skin cancer.
Atypical Moles are unusual-looking benign (noncancerous) moles, also known as dysplastic nevi (the plural of “nevus,” or mole). Atypical moles may resemble melanoma, and people who have them are at increased risk of developing melanoma in a mole or elsewhere on the body.
The higher the number of these moles someone has, the higher the risk. Those who have 10 or more have 12 times the risk of developing melanoma compared with the general population.
Basal Cell Carcinomas (BCC) are abnormal, uncontrolled growths or lesions that arise in the skin’s basal cells, which line the deepest layer of the epidermis (the outermost layer of the skin). BCCs often look like open sores, red patches, pink growths, shiny bumps, or scars and are usually caused by a combination of cumulative and intense, occasional sun exposure.
Basal Cell Carcinomas almost never spreads (metastasizes) beyond the original tumour site. Only in exceedingly rare cases can it spread to other parts of the body and become life-threatening. It shouldn’t be taken lightly, though: it can be disfiguring if not treated promptly.
Basal Cell Carcinomas are the most common form of all cancers. basal cell carcinoma
Both basal cell carcinoma is also known as a non-melanoma skin cancer
Squamous Cell Carcinoma (SCC) is an uncontrolled growth of abnormal cells arising in the squamous cells, which compose most of the skin’s upper layers (the epidermis).
SCCs often look like scaly red patches, open sores, elevated growth with a central depression, or warts; they may crust or bleed. They can become disfiguring and sometimes deadly if allowed to grow.
SCC is mainly caused by cumulative exposure to the sun’s ultraviolet (UV) radiation over the course of a lifetime.
SCCs may occur on all areas of the body including the mucous membranes and genitals but are most common in areas frequently exposed to the sun, such as the rim of the ear, lower lip, face, balding scalp, neck, hands, arms and legs. Often the skin in these areas reveals telltale signs of sun damage, including wrinkles, pigment changes, freckles, “age spots,” loss of elasticity, and broken blood vessels. squamous cell carcinoma.
Squamous cell carcinoma is also known as a non-melanoma skin cancer.
Melanoma is the most dangerous form of skin cancer, these cancerous growths develop when unrepaired DNA damage to skin cells triggers mutations (genetic defects) that lead the skin cells to multiply rapidly and form malignant tumours.
These tumours originate in the pigment-producing melanocytes in the basal layer of the epidermis. Melanomas often resemble moles; some develop from moles. The majority of melanomas are black or brown, but they can also be skin-coloured, pink, red, purple, blue or white.
Melanoma is caused mainly by intense, occasional UV exposure (frequently leading to sunburn), especially in those who are genetically predisposed to the disease.
If melanoma is recognized and treated early, it is almost always curable, but if it is not, cancer can advance and spread to other parts of the body, where it becomes hard to treat and can be fatal.
While it is not the most common of skin cancers, it causes the most deaths. Melanoma kills about one in six patients. melanoma.
Merkel Cell Carcinoma (MCC) is a rare, aggressive skin cancer that is at high risk of recurring and spreading (metastasizing) throughout the body, with most recurrences taking place within two years after diagnosis of the primary tumour. While the disease is very rare, it results in death in 30% of patients
MCC most often arises on sun-exposed areas in fair-skinned individuals over age 50. Its name comes from the similarity of these cancer cells to normal Merkel cells in the skin that are thought to be associated with touch sensation.
Every Australian is at risk of skin cancer, though the risk increases as you get older.
People who have had skin cancer previously are at risk for developing others over the years, either in the same area or elsewhere on the body.
For these patients, regular screening and full body mapping should be routine so that not only the site(s) previously treated are monitored, but the entire skin surface can be examined and compared for changes.
Skin cancers on the scalp and nose are especially troublesome, with recurrences typically taking place within the first two years following surgery.
Both long-term sun exposure over your lifetime and occasional extended, intense exposure (typically leading to sunburn) combine to cause damage that can lead to skin cancer.
Almost all skin cancers occur on parts of the body excessively exposed to the sun — especially the face, ears, neck, scalp, shoulders, and back.
The risk of skin cancer increases with age both as a result of cumulative sun exposure and the degenerative nature of aging.
The incidence increases for both males and females over 50 years old, but as the number of new cases has increased sharply each year in the last few decades, the average age of patients at onset has steadily decreased.
The tendency to develop can also be inherited, people who are at the highest risk have the following genetic features:
Skin tumours can develop
It is not possible to pinpoint a precise, single cause for a specific tumour, especially one found on a sun-protected area of the body.
The disease is rarely seen in children, but occasionally a teenager is affected.
Over time solar keratoses may regress, fade, stay the same, or change.
Beware of the following developments:
If you notice any of the features mentioned above.
Sunspots can become dangerous. Skin cancer called Squamous Cell Carcinoma can develop from sunspots in people who are at risk.
As many as 65% of all primary squamous cell carcinomas arise from previously diagnosed solar keratoses in high-risk individuals.
Solar keratoses are diagnosed clinically based on their characteristics, and in suspicious cases, a biopsy may be required to rule out malignancy.
The greatest cause of skin cancer is overexposure to ultraviolet (UV) radiation from the sun.
Sunburn causes 95% of melanomas, the most deadly form of skin cancer.
In Australia, on an average summer weekend, many people get sunburnt when they are taking part in watersports and activities at the beach or a pool, as well as gardening or having a barbeque, etc.
Sunburn is also common on cooler or overcast days, as many people mistakenly believe UV radiation is not as strong. This is untrue – you can still be sunburnt when the temperature is cool.
Sun exposure that doesn't result in burning can still cause damage to skin cells and increase your risk of developing skin cancer. Evidence suggests that regular exposure to UV radiation year after year can also lead to skin cancer.
Become familiar with the look of your skin, so you pick up any changes that might suggest a skin cancer.
Look for:
Frequently, two or more of these features are present in one tumour.
If you observe any of the warning signs or some other worrisome changes in your skin, consult your GP immediately.
The sooner a skin cancer is identified and treated, the better your chance of avoiding surgery or, in the case of a serious melanoma or other skin cancer, potential disfigurement or even death.
It is also a good idea to talk to your doctor about your level of risk and for advice on early detection.
There is currently no formal screening program for skin cancers in Australia.
It is generally recommended that you have a skin cancer screening test once every two years. This should be more regularly performed if you are at risk.
Higher risk patients are those mentioned above.
It is important to check your skin regularly and check with your doctor if you notice any changes.
Your doctor may perform a biopsy (remove a small sample of tissue for examination under a microscope) or refer you to a specialist if he/she suspects a skin cancer.
Skin cancers are almost always removed. In more advanced skin cancers, some of the surrounding tissue may also be removed to make sure that all of the cancerous cells have been taken out.
Common skin cancers can be treated with
They can also be removed with
It is not possible for a doctor to predict the exact course of a disease. However, your doctor may give you the likely outcome of the disease. If detected early, most skin cancers are successfully treated.
In 2013, 2209 people died from skin cancer in Australia, 1617 from melanoma and 592 deaths from non-melanoma skin cancers.
The five-year relative survival rate for melanoma is 89% for Australian men and 94% for Australian women.
For best protection, we recommend a combination of sun protection measures:
Be extra cautious in the middle of the day when UV levels are most intense.
Evidence suggests that childhood sun exposure contributes significantly to your lifetime risk of skin cancer. Cancer Council Australia recommends keeping babies out of the sun as much as possible for the first 12 months.
Where this is not possible, parents and carers should minimise exposure by:
There is no evidence that using sunscreen on babies is harmful, although some babies may develop minor skin irritation. Try sunscreen milk or creams for sensitive skin which are less likely to irritate the skin. As with all products, the use of any sunscreen should cease if any unusual reaction occurs.
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